DOTAP Chloride, Transfection Reagent

£94.05 – £608.95 Price ex. VAT

DOTAP Chloride (N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride) is a widely used cationic liposome-forming compound for in vitro and in vivo transfection of DNA, RNA and other negatively charged molecules.

Pack sizes: 25mg, 100mg,  500mg

Send us an enquiry: parkinfo@parkscientific.com

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SKU: 14475 Categories: , , ,

Description

DOTAP Chloride (N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride) is a widely used cationic liposome-forming compound for in vitro and in vivo transfection of DNA, RNA and other negatively charged molecules. DOTAP encapsulates the nucleic acids to form a stable complex spontaneously by means of electrostatic interaction, facilitates cell attachment, internalization by endocytosis as well as endosomal escape by proton sponge. It has been used in the formation of Lipid Nanoparticles (LNPs) or Nanostructured Lipid carriers (NLCs) in the development of mRNA vaccines such as COVID-19 vaccine and drug delivery systems. This product is for research use only.

Contact us at parkinfo@parkscientific.com to know about our cGMP grade DOTAP Chloride manufactured under 21 CFR part 210,211.

KEY FEATURES:

  • High efficiency and reproducibility
  • Cost effective and easy to use
  • Scalable
APPLICATION(S): Transfection of DNA, RNA, and oligonucleotides, Lipid Nanoparticles (LNPs), Nanostructured Lipid Carriers (NLCs), mRNA vaccine development, Drug delivery system development
SHIPPING REQUIREMENTS: Dry Ice
APPEARANCE: White to off white solid
MOLECULAR WEIGHT: 698.54
STORAGE: Store powdered material at -20°C, protect from moisture and light.

Additional information

Size

25 mg, 500 mg, 100 mg

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