DODMA (1,2-dioleyloxy-3-dimethylaminopropane), Transfection Reagent

£59.85£359.10 Price ex. VAT

DODMA (1,2-dioleyloxy-3-dimethylaminopropane) is an ionizable cationic lipid with a protonatable tertiary amine head group that shows positive charge at low pH. DODMA is highly efficient at encapsulating nucleic acid to form lipoplexes during synthesis by reducing the physiological pH, which readily passes through the cell membrane. These properties make DODMA highly suitable for transfection and drug delivery applications.

  • Efficient delivery of plasmid DNA, siRNA/miRNA and CRISPR/Cas9 components
  • Cost-effective
  • Flexibility and reproducibility

Send us an enquiry: parkinfo@parkscientific.com

Pack sizes: 25mg, 100mg,  500mg

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Description

DODMA (1,2-dioleyloxy-3-dimethylaminopropane) is an ionizable cationic lipid with a protonatable tertiary amine head group that shows positive charge at low pH. DODMA is highly efficient at encapsulating nucleic acid to form lipoplexes during synthesis by reducing the physiological pH, which readily passes through the cell membrane. These properties make DODMA highly suitable for transfection and drug delivery applications.

KEY FEATURES

  • Efficient delivery of plasmid DNA, siRNA/miRNA and CRISPR/Cas9 components
  • Cost effective
  • Flexibility and reproducibility

SYNONYM: 1,2-Dioleyloxy-3-dimethylaminopropane

Contact us at parkinfo@parkscientific.com to know about cGMP grade DODMA manufactured under 21 CFR part 210,211.

APPLICATION(S): DNA, SiRNA, mRNA transfection, Drug delivery, Gene therapy

CAS Number: 104162-47-2
Linear Formula: C41H81NO2
APPEARANCE: Colourless to light yellow liquid

MOLECULAR WEIGHT: 620.09

HANDLING: Protective gloves, safety glasses
STORAGE: -20°C
SHIPPING REQUIREMENTS: Dry Ice

Additional information

Size

25 mg, 500 mg, 100 mg