Picrosirius Red Stain Kit

£355.30 Price ex. VAT

Picrosirius Red Stain binds specifically to collagen fibrils of varying diameter that is used to distinguish collagen Type I from Type III. Picrosirius Red Stain will quantify the amount of collagen in a given area of myocardial tissue. Picrosirius Red staining is also useful in the quantitative aspect of liver fibrosis by measuring a change in collagen proportion stained as red (Jang et.al., 2014).

500ml kit = stains upto 200 slides

SKU: 24901-500 Categories: , ,

Description

Picrosirius Red Stain binds specifically to collagen fibrils of varying diameter that is used to distinguish collagen Type I from Type III. Picrosirius Red Stain will quantify the amount of collagen in a given area of myocardial tissue. Picrosirius Red staining is also useful in the quantitative aspect of liver fibrosis by measuring a change in collagen proportion stained as red (Jang et.al., 2014).

Kit contains:
Solution A – Phosphomolybdic Acid (250ml or 500ml)
Solution B – Picrosirius Red F3BA Stain (250ml or 500ml)
Solution C – 0.1 N Hydrochloride Acid (250ml or 500ml)

500 ml kit stains up to 200 slides

Reference(s):
Fujita, K. et al. A new rabbit model of impaired wound healing in an X-ray-irradiated field. PLOS ONE 12, e0184534 (2017). doi:10.1371/journal.pone.0184534
Muto, T. et al. Temporary inductions of matrix metalloprotease-3 (MMP-3) expression and cell apoptosis are associated with tendon degeneration or rupture after corticosteroid injection. Journal of Orthopaedic Research 32, 1297–1304 (2014). doi:10.1002/jor.22681
Jang, Y. O. et al. Histological improvement following administration of autologous bone marrow-derived mesenchymal stem cells for alcoholic cirrhosis: a pilot study. Liver International 34, 33–41 (2014). doi:10.1111/liv.12218
Foster, B. L., Sheen, C. R., Hatch, N. E., Liu, J., Cory, E., Narisawa, S., … & Millán, J. L. (2015). Periodontal defects in the A116T knock-in murine model of odontohypophosphatasia. Journal of dental research, 94(5), 706-714.
Rodrigues, T. L., Nagatomo, K. J., Foster, B. L., Nociti Jr, F. H., & Somerman, M. J. (2011). Modulation of phosphate/pyrophosphate metabolism to regenerate the periodontium: a novel in vivo approach. Journal of periodontology, 82(12), 1757-1766.
Kelly DJ, Chanty A, Gow, RM, Zhang Y, and Gilbert RE (2005) Protein Kinase CInhibition Attenuates Osteopontin Expression, Macrophage Recruitment, and Tubulointerstitial Injury in Advanced Experimental Diabetic Nephropathy, J Am Soc Nephrol 16: 1654 –1660.
Wenxuan Liu, Lan Wei-LaPierre, Alanna Klose, Robert T Dirksen, Joe V Chakkalaka Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctions eLife  2015;4:e09221
 
Hazards: Irritant
Handling: Gloves, chemical goggles
Storage: Store at room temperature

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